Accelerating Pharmaceutical Innovation
Through Data-Driven Multi-Omics Discovery

We partner with top-tier global pharmaceutical organizations and emerging biotech leaders to de-risk R&D pipelines, advance companion diagnostic programs, and compress development timelines from target identification through regulatory submission.

Scroll to discover

Transforming Biological Complexity into Commercial Pipeline Value

Calivanta BioPharma builds AI-powered molecular design platforms that drive in-silico drug discovery, protein engineering, and precision medicine — across our own pipeline and in partnership with pharmaceutical companies worldwide.

12+
Active Pharma Partners
5
Proprietary Platforms
3
Continents
Ongoing
Active Development Pipeline

AI-Driven Drug Discovery, Protein Design, and Bioinformatics Platforms

Our proprietary platforms combine molecular simulation, computational protein design, genomics, and bioinformatics to speed up therapeutic discovery — from in-silico target validation to precision medicine biomarker development.

Scientist examining samples in Calivanta BioPharma genomics laboratory

Target Discovery & Validation

CaliOmics combines multi-omics analysis with molecular dynamics simulation to identify and validate novel therapeutic targets. By integrating CRISPR screening data, GWAS meta-analyses, and proprietary pathway models, we cut target attrition and speed up hit-to-lead timelines.

Biomarker Discovery & Companion Diagnostics

TherAlign uses machine learning to identify predictive biomarkers across solid tumors and hematological malignancies. Several biomarker panels are currently in co-development with pharma partners, supporting precision medicine and companion diagnostic programs.

Precision Medicine & Immuno-Oncology Analytics

ImmunoScope provides end-to-end immune profiling for IO drug development, analyzing T-cell receptor repertoires, tumor microenvironment transcriptomics, and circulating immune cell dynamics. Now in pilot programs with three major pharma partners developing next-gen checkpoint inhibitors and CAR-T therapies.

Mechanism of Action & Regulatory Strategy

PathwayPredict applies systems pharmacology and network analysis to deconvolute drug mechanisms of action and predict off-target effects. ClinicalConnect pulls real-world evidence from EHR and claims data to optimize trial design and support FDA and EMA regulatory filings.

Enterprise-Grade Infrastructure and Proprietary Bioinformatics Pipelines

We run dedicated high-performance compute infrastructure built for molecular simulation and multi-omics workloads. End-to-end encryption, SOC 2 Type II, GDPR, and HIPAA compliance. Elastic scaling from pilot studies to population-level analyses.

High-performance computing data center at Calivanta BioPharma

CaliOmics Analytics Engine

Proprietary computational framework integrating 5 omics layers with a multi-layer computational approach, trained on curated public and partner-proprietary datasets

Enterprise Security & Compliance

SOC 2 Type II certified, HIPAA-aligned data handling, GDPR-compliant processing, and strict IP firewalls with partner-specific access controls

Scalable Cloud-Native Architecture

Elastic infrastructure supporting projects from single-cell RNA-seq pilot studies to multi-cohort, population-scale WGS and metabolomics analyses

Tailored Solutions for Global Pharmaceutical and Biotech Partners

We advance our proprietary pipeline while partnering with global pharma organizations — from platform co-development with leading companies to strategic collaborations with emerging biotech innovators using our discovery engines.

Top-Tier Global Pharmaceutical Companies

Multi-year platform co-development, precision medicine joint ventures, regulatory submission support (FDA/EMA), and enterprise-scale RWE analytics for portfolio prioritization

Emerging Biotechnology Firms

On-demand access to enterprise-grade discovery platforms, flexible milestone-based engagements, and technical due diligence for financing rounds

CROs & Academic Medical Centers

White-label bioinformatics pipeline licensing, clinical trial biomarker monitoring, translational research frameworks, and grant-supported co-development of novel analytical methods

Worldwide Infrastructure Supporting Multi-Continent Partnerships

Headquartered in Switzerland with operations in Europe and North America. Our regional teams provide local regulatory expertise, data sovereignty compliance, and dedicated partnership management across US and European markets.

Switzerland headquarters

Switzerland

Global Headquarters & European R&D Hub

Europe

European Operations Center & EMA Regulatory Affairs

North America

North American Business Development & FDA Strategy Office

Our Basel headquarters coordinates global R&D and partner engagement. Our European and North American offices handle local regulatory strategy, data sovereignty, and account management across all major pharma markets.